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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81487624f077870963ceab190a8b3d08339a1bc4e33fd249e56b26a20e7c86c9' 
  AND token = 'mus4g81LXvezCsT2ndLdZu1kmkacJDtdAYESp9tOG8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}