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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f5050f2e09dcbd6ef6251ed3ab1235195f68ceb52c216f5a0b6d149c9b4f854' 
  AND token = 'GrbqiKpi+HhoS9iBg4VfrGIxgyWY7jFYDwAaH9G6prw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}