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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8efc1c67fdcf2cbabcf06899d18598249a64f5ced5d5cb84b29d848d16f382' 
  AND token = 'yNX2UcYeDfJDAgIX6uAeoNfK9Xz1WviN+hvzf0ncvbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}