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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57601d065dd6f61bb5544f46ffdcdc504c043e84d111750b88ece27df60acab' 
  AND token = '/cjPAZT7Xb9GCL/n/GEzf+rt6eUcNeZaTqviTJ9COtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}