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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ae03c4f20f8c535a080ac48a4e3733efeededbfadfc1e6107020c480b9e6df' 
  AND token = 'pam9ZCpaNDC8nQD8qqEALPj8hlM0OpmiGe/Dp5w1PvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}