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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84a2a547940cbd0b819f4312add0485cd663c1e3dfab2a328e0633eeee910cef' 
  AND token = 'L/yZssRcYy+m6rfsIYYzLF/rnWOO2cKLWtbcWp6hPyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}