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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d9004b785868004eae584e0f4162227ae11c9cc2946fe9fedde1ff32586da6' 
  AND token = 'U0XITKGtUEabdMokerH1G1KL+2w/BT89TeG7rUYOGog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}