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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539881a8a38536af428a554f6a4704df1ce33ee0505cff78d5d483f26ec6dc33' 
  AND token = 'wUizCJQ97V0EzeDeTCP9drlzNW1qq0YZTSqlix6FY3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}