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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429052d5be0a3d8d1a0a446cc07759ab4e854bed98f7346e80473c4a89d85a61' 
  AND token = 'A5z6MUQBMnkCyb5OjgOuF0LxZ1mx+KjkPmBhj1MRImg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}