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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46125e9b18f810f143700db42c21ccaf3314c297d6333d7234c132d7c4da0cd5' 
  AND token = 'qyN1NOQMeiozeNINMCXGPwNAv8FxCZAVdZygwja4+bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}