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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3397fed0def994ca6ef337195a2b80f45ec97e5dfecbab626dbab4c901feec9' 
  AND token = 'ZoM3cGi/roC76wB/RFYAThT6rgkz/LESOT16eDP31NM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}