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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c54a4e304ce2811a80f3aa0c4dc944ee57bb4ed4034bde74312dd1b671fa618' 
  AND token = '0P0A2DYoXqoHScUR0B3b/X+sJKr5qj2PhbPy1IfEN/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}