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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041f5727b6c6093ef02e23c2b2c09b8aeffb661b9f1210665be56d4658b36314' 
  AND token = 'b2uCWcZRiEdABcHza24PqUCB7pS1+0CcnSC3A83mS34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}