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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ad45c4fffd6f5405e80a5c8753e89daec4519ed2eb80b59c5685ca295e7937' 
  AND token = 'ncphk8XpKniWvEs3smFhcO0V3mp9573aItB66X3DR0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}