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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '952ee7e135f788a896d9b43fa9ee9330993a31412a8aa3587f64e5c9ef7f6540' 
  AND token = '8GzicyIPKpBrK85+Qpr0k2t4xgmBZxpKVBoRaSyaWFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}