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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5234d54ec2060848255ed8ad354a98995c34221fe2348c0aae7ca1d340a6e6fd' 
  AND token = 'o4uI1FqetHGyYnPXYKcMYZ5fyBHUBqumZTepJt2sdyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}