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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ecddfa70b0d0a0ebdd7d326326cadbe6c89d6064778ad2a8c867227311a42ad' 
  AND token = 'pHgu4MyiA589XeN8eiwZ4hMM5Lyh4rSvEnfOnrY8QDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}