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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cbcb0a48c526fcd38346f9cda4afa24f0ddcdcbf500f55fd5e38d11525b69a' 
  AND token = 'drfOGBggxCKRiQzFTHvhUw9bVT763THmcsy1/2peCIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}