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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163f38ffe51ce023ad82dea40396d860ce99d47a19781f04175b89f2f33a7b9b' 
  AND token = 'fHHfJPjbRgDMzz6+qPqY6VMT3j380Pmc/xNR5wTu3U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}