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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fffda844fb13abb463b4af01644b485bc90e2d64221c6d8110227257787e0fd' 
  AND token = '/yCiQUCALuLyBTCWSiCRyRlCyXspixc00AwpjH7jpRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}