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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4852b82a7e92bada3cd98cbf2fcb2ab6ab09e192805e418ee40e5a7ec09bb2bb' 
  AND token = 'EM1D50yOekxw4/24PbT9+J6qLumnyCYGhRsXbnMBINA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}