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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5d1f67e4a256a144952b927a9f7f8df06867c219cda16637dcf36e7266cb73' 
  AND token = 'Rv0M0wM28XEx3hTJrAGigUidSIFqTAe7nYpT+S74ciI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}