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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0113aec266b600e30b0d64019de152f55183d32cdad42e7e1ae65baf50e5446' 
  AND token = 'Q4N0M2wE/Ond9YSt3DlozcIz5QWpgcv077+eXrSrqV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}