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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6245a32bd3b357e0fa0c5676afcd2228ed8260693e8682d60d78b2955b4647c' 
  AND token = 'TleL/uKeHDyzDLRD1yLywoDcHMQhUdvsAAAV1LY/H18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}