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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b33f576cd93c62fc84b3fb448000f4978e987b4fdbce2ca6e62a498b605cc10' 
  AND token = 'L6nlV41ym44BBv9oR1ZcZ45+2ltOJ6i0hPrqmyWVKL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}