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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9296791f474a2eee60b1b1a841f3aeaaccab78350b7a9719f09a835a73af5cb9' 
  AND token = 'cAi/9kSo871SEu1HC46UoakRuSSE/wptM1kt7pz3EkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}