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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '411e0069dfb8b74ff6568e729e2d12cfc069cecdc9721a7188bb98f62dd84c9a' 
  AND token = 'zJI2Fbfi/uHi7uNFp/oCWt0myrfpgpf4KNfA0T2LWnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}