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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '592cfc76288d7f0218d19471654031a7fe824dceefd1e1dc02c3e629cb67791d' 
  AND token = 'WMMowwtFIjzUa2kw559tlApQFiblgXfI26isCvdyUUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}