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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cac26c91c75d39032636a4d1e83adc7ee136151c28a1afcd06d177cb765d4cdc' 
  AND token = 'F113+i3coCrc55NSp1p9MrcICkqqNApQVZltsZZs9zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}