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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41147982164c3972b165cce9e63afefc0ea8ccc714ae2001480709abe2ff259e' 
  AND token = '5qJTbx8am5mdLqO7bcHVFhmdXDPuiEwvi0OYel73RMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}