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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b405d9b6584b1327eedf2f0da08a7d3241e6d8c22adebd38e153a83d7d0901' 
  AND token = '9stjjINoFJXoDA0eLRRQgRnssA0lWgvp9MBQzFLotr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}