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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad8ecaf2fd285b083a8dd1b9920dcd98635edb4dfd2e24c2e02df154382362c' 
  AND token = '2p7HQ4rCsOXqba3KNAW7Y4y1LC45rwmLUHQkKKXtQII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}