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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc80859e469fcde53eb81605091f19ab4ac12bbfc28f9ee2a17fc23b0609f87' 
  AND token = '+ICFgc2/uUzzc1iR4IIBRwH11FqIpbCTBgduQddJi/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}