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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf289415d518af66dd6e71e54e9539c00dd0bc583941de12a309fde95ed5b728' 
  AND token = 'Yl+EzlutcTzCslKUKwDPdXv+nnkLndsVKzaMLcOm4rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}