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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65597f0fd70c65cd39f72b6d6eef751397d76b00062c36802e2446f6728e6cf' 
  AND token = '65v1IAhmCkbti8f9JC5PKewW383UqcZ6ZqgUd9OxFHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}