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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c849c5886fc28a23186ccde0b891f2fc93aa3036e1532d038607dffc88e4352' 
  AND token = 'qNtaFk5IcPgwc9wfYHWAP0n5n1d7fdODpw4TUBH8G0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}