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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d3c0e5eb06f7342374408a12bde462d8f56a5fcec850548b972c644ede0d41f' 
  AND token = 'N6tHL4is/3Q+UCGc65KpMTFkKHNJR7FBWuS0c2SjIOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}