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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ec2e002145051f1194e39b23d5f02ba848633afaf1fb5f1366d05a7a269c66' 
  AND token = 'EB8CrF7UWjfQf+AvsqvVD727VFyRD/KvfC6fms/EiL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}