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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85250cc10e1813e5aec2eb03644ef89cd27308448a983900dd363835e5182973' 
  AND token = 'jbroJyyh7Aeu6zP5KPKfrfKOgb6ZsAccq7OP8oLAOBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}