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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b1959c0e871c1f800b768cc3a0d5de5979c386fd7070b1a01cd75567897b6fd' 
  AND token = 'ZWT0HIQL2a+/fIXZq/flvT0Jjxi2k9Kb3OtrKRZv3XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}