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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f53b113ac217338e26efa31851f91f396e527f49b3e65bea7a8cb6224de8b7c' 
  AND token = '4udP4gANEY03qBOBzoAK/HcB/aN/+PaNW9We9n4jqM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}