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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10f709c59748969786e80fd11cfaca7c3c970ef627c36baf20ce087d16e98da' 
  AND token = 'MIQiFSN14/A3EY8lfVGpWTBW//pOQCeKNlTYQGUg6Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}