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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819cbe0f4c53185d1c9fcf90b23e7ada21f84348670b68bdc027f89d4ff49778' 
  AND token = 'NJsCnAUAFtuiBhf6nFHmEDONS5sduxj4D2Oags4EVT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}