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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed54645c06fee75b39c18ffe5ff27eb82e96a33f190ad3ec8d112f7daaf15d3e' 
  AND token = 'hCSRy5wY+Y2hspH4R/6V1I1L4LOndW1lMKsOej11/p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}