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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71860a89aebcc060d825303e5edc2e63214b56d2f2b599eb477ebe3b0562d0ff' 
  AND token = 'SdEatCYVJvFM1DcDveYuqcHe9+ERaIIV2C2fk4P8BXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}