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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '245dbf33fc5afa714aa04787ce64af837c2933ba2245467f7280c518accdf8b1' 
  AND token = 'V6x+m9U9EXaeI191VVPmjTbcXBh/Gl4D73KohMBXq1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}