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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e94346739da64d0a4755d01439904114394cc90850aad5f9b4f2f0641b0451f' 
  AND token = 'Ob/2UixVqK+oXHP3/cDVs5CaN7XrbG2ED6MHa5hu1hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}