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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5198cd2ce0defb5b31b39c29bf304b646e2a99357049e54274fe10c89e72b726' 
  AND token = 'ueDdYA0EFfOynEF1mUdi0ylJbyeuqTezpT/2VwRZlRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}