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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd645042a3fe997e43356757f6609638d881d81772be4da25a2817307faa78e9e' 
  AND token = 'cbZyqZ5oJR+BFsGQeBGWOOH/29MExxN6i/rVQTA2nt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}