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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d9eee3a257f4ccd08d5141379b95bb59f2e7aab0d399dc0d941261648b6c371' 
  AND token = 'ak+V/HLbjq6qaRY9dlg5yJgyocKQYdZ3Pa06hyUktWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}